Orthobiologix Clinic India and Dubai Joint Pain Treatments 16 e18774 - Orthobiologix Clinic

Platelet Rich Plasma

The Next-Generation Regenerative Medicine for Musculoskeletal Disorders
PRP or Platelet Rich Plasma therapy is an injection of patient’s own platelets from their own blood to accelerate the healing of their damaged or degenerated tissue( like tendons/ligaments/joints or muscles). This concentrated platelet injection releases lot of growth factors as well as other healing factors in the damaged area  leading to enhanced healing of damaged tissue.

Since the concentration of platelets and in turn growth factors is more in the PRP, the healing is much faster.

The process of PRP is very simple and involves drawing patients blood, separating the plasma, concentrating the platelets and then injecting it precisely into the damaged area.

The procedure is OPD based and lasts for less than an hour. Recovery period is short. Most patients report relief of symptoms within a few weeks.

Platelet-Rich Plasma (PRP) Injection

PRP is plasma with highly concentrated platelets. As a concentrated source of autologous platelets, PRP contains (and releases through degranulation) several different growth factors and other cytokines that stimulate healing of bone and soft tissue.

Platelets are a specialized type of blood cell involved in injury healing. Platelets also contain large reservoirs of natural growth factors that are essential for the cell recruitment and multiplication involved in wound healing. The normal concentration of platelets circulating in our blood is 200,000 per microliter. Current evidence suggests that platelet count in Platelet Rich Plasma should be near or exceed 1,000,000 platelets per microliter which is a concentration of 5x. PRP is made in the clinic using a centrifuge that separates the blood components and allows us to discard unwanted elements from the blood and to keep the platelets, growth factors, cytokines, and plasma that are used for PRP. The centrifuge takes less than 10 minutes to concentrate the platelets after blood is drawn from the patient.

What are the clinical indications for using PRP?

PRP is being studied and used for many orthopaedic conditions.

For example, there are over 30 levels, studies published showing that PRP is a better treatment than steroid or hyaluronic acid injection for knee osteoarthritis. PRP has now been used and studied for virtually every joint tendon, ligament injury in orthopaedics. PRP has also been shown to be effective in treating back pain from various conditions such as disk disease, or facet arthrosis.

What growth factors and cytokines are in PRP?

Some of the growth and healing factors found in PRP include:

  • Platelet Derived Growth Factor (PDGF)
  • Fibroblast Growth Factor (FGF)
  • Vascular Endothelial Growth Factor (VEGF)
  • Interleukin 8 (IL-8)
  • Transforming Growth Factor Beta (TGF-b)
  • Insulin like Growth Factor 1, 2 (IGF-1,2)
  • Epidermal Growth Factor (EGF)

What are the clinical indications for using PRP?

Tendonitis (Chronic tendonitis or partial-thickness tears)

  • Rotator cuff
  • Biceps
  • Golfers/Tennis elbow
  • Tendonitis around the thigh (Gluteus medius, hamstring, piriformis syndrome)
  • Patellar or quadriceps tendonitis
  • Tendonitis around the ankle (Peroneal, Tibialis posterior)
  • Achilles
  • Plantar fasciitis
Ligament Injury

  • Ulnar collateral ligament injury of the elbow
  • Medial collateral ligament injury of the knee

Degenerative Joint Disease

  • Knee osteoarthritis
  • Shoulder osteoarthritis
  • Elbow osteoarthritis
  • Wrist osteoarthritis
  • Ankle osteoarthritis
  • Hip osteoarthritis
  • Symptomatic articular cartilage injury

What happens after the PRP injection in the clinic?

Most patients will have some soreness after the injection that should decrease rapidly. Patients should not take aspirin or other NSAID medications after the procedure because they may block the effect of PRP . Patients can use Paracetamol that doesn’t  block the inflammatory process. Patients should refrain from significant physical activity or sports activities for a week after the procedure. Patients are re-evaluated often after the procedure to make sure their recovery process is proceeding according to plan.

Orthobiologix Clinic India and Dubai Joint Pain Treatments 5 - Orthobiologix Clinic

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